CIRCLE TEAM PRODUCT EXPERIENCE

Michael Forman

  • Surgical Lasers – CO2 and Nd:YAG
  • Optical Blood Diagnostics/Johnson & Johnson
  • Interventional Cardiology Catheters – Balloon Catheters and Guide Catheters/Schneider USA
  • X-Ray Catheters/Xoft microTube
  • Distal Protection Catheters/ev3
  • Endovascular mitral valvuloplasty Catheters/ev3
  • Brachytherapy Catheters and Devices/Cobblestone Medical Technologies
  • Interventional Neuroradiology Catheters for Delivery of Drugs
  • Drug Delivery Catheters/Schneider USA
  • Intraosseous Drug Delivery Device/ Vidacare
  • Remote Temperature Sensing
  • Laser Processing of Catheters/Schneider USA/Boston Scientific
  • Tissue Processing Device for Pathology/Cobblestone Medical Technologies
  • Sternal Bone Marrow Biopsy Device/Cobblestone Medical Technologies
  • Tissue Processing Device for Pathology/Cobblestone Medical Technologies

 

Ken McCuen

  • Microwave Generator for Tissue Ablation
  • Remote Sensing of Flow in Implanted Shunt - EUNOE
  • RF Ablation Instrument
  • Intraosseous Drug Delivery Device - Vidacare
  • Radiance System for System Cooling to Prevent Stroke
  • Cryovascular System for Cold Balloon Angioplasty
  • Remote Temperature Sensing
  • Temperature Measurement & Control

 

Dan Mufson

With years in Big Pharma and leading drug delivery companies, Dan has expertise in the formulation and manufacturing of all dosage forms--aerosols, injections, ophthalmics, tablets and topicals. He headed R&D for two major drug delivery companies, Liposome Technology, Inc. and Alexza Molecular Delivery Corporation.

Some relevant experience is highlighted below:

  • Drug Delivery Systems (DDS):
    • Liposomes and Stealth®Liposomes
    • Thermal aerosol generators
    • Intranasal peptide delivery
    • Controlled release tablets
  • Combination (Drug-Device) products:
    • Thermally generated aerosols
    • Cell separator (Biological-Device)
    • Polymeric ocular systems
    • Iontophoresis
  • Device Products:
    • First-aid gel
    • Contact lenses
    • Heart valve
    • Light activated polymers

Product Development:

Many of his clients at APOTHERX have been companies developing their first product for whom he served to completely coordinate all of the chemistry and pharmacy issues (CMC) leading to their first IND(s). Several of these formulations have been approved including Prialt® (Ziconotide intrathecal infusion) (Neurex/Elan); Abreva® (docosanol creme) (Lidak/Avanir) and Panretin® (alitretinoin gel) (Ligand). He formulated the first antisense oligonucleotide and the first vomerophermone to be administered to man.

BSC Laser
Bonded Balloon
Catheter

Cryovascular
Controller

 

Opthalmic
Injector

 

Catharos
Catheter

CVIS System

CVIS System